If I have a span, say:
hereismytext
How do I use JavaScript to change "hereism
Using innerHTML is SO NOT RECOMMENDED. Instead, you should create a textNode. This way, you are "binding" your text and you are not, at least in this case, vulnerable to an XSS attack.
document.getElementById("myspan").innerHTML = "sometext"; //INSECURE!!
The right way:
span = document.getElementById("myspan");
txt = document.createTextNode("your cool text");
span.appendChild(txt);
For more information about this vulnerability: Cross Site Scripting (XSS) - OWASP
Edited nov 4th 2017:
Modified third line of code according to @mumush suggestion: "use appendChild(); instead".
Btw, according to @Jimbo Jonny I think everything should be treated as user input by applying Security by layers principle. That way you won't encounter any surprises.