Including COM Objects:
heat generates all most (if not all) the registry entries and other configuration needed for them. Rejoice!
Including Managed COM Objects (aka, .NET or C# COM objects)
Using heat on a managed COM object will give you an almost complete wix document.
If you don't need the library available in the GAC (ie, globally available: MOST of the time you do not need this with your .NET assemblies anyway - you've probably done something wrong at this point if it's not intended to be a shared library) you will want to make sure to update the CodeBase registry key to be set to [#ComponentName]. If you ARE planning on installing it to the GAC (eg, you've made some new awesome common library that everyone will want to use) you must remove this entry, and add two new attributes to the File element: Assembly and KeyPath. Assembly should be set to ".net" and KeyPath should be set to "yes".
However, some environments (especially anything with managed memory such as scripting languages) will need access to the Typelib as well. Make sure to run heat on your typelib and include it. heat will generate all the needed registry keys. How cool is that?