The easiest way to compute the correct mouse click or mouse move position on a canvas event is to use this little equation:
canvas.addEventListener('click', event =>
{
let bound = canvas.getBoundingClientRect();
let x = event.clientX - bound.left - canvas.clientLeft;
let y = event.clientY - bound.top - canvas.clientTop;
context.fillRect(x, y, 16, 16);
});
If the canvas has padding-left or padding-top, subtract x and y via:
x -= parseFloat(style['padding-left'].replace('px'));
y -= parseFloat(style['padding-top'].replace('px'));