I can\'t believe that neither a Google or SO search has turned up a definitive answer or even much discussion for this, but:
Is it possible to edit/customize keyboar
Inspired by @jcollum's answer, here is yet another Karabiner private.xml definition, this one implementing the specific Eclipse key bindings in the original question. See also keyboard shortcut toggling answer on apple.stackexchange.com.
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Custom via private.xml
ChromeLike
com.google.Chrome
com.vivaldi.Vivaldi
org.epichrome.app.
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Remap debugger keys in Chrome (Eclipse)
Change consumer keys to function keys matching Eclipse shortcuts
private.app_chromelike_switch_consumer_to_eclipse_debugger
ChromeLike
__KeyToKey__ ConsumerKeyCode::KEYBOARDLIGHT_LOW, ModifierFlag::NONE, KeyCode::F11
__KeyToKey__ ConsumerKeyCode::KEYBOARDLIGHT_HIGH, ModifierFlag::NONE, KeyCode::F10
__KeyToKey__ ConsumerKeyCode::MUSIC_PREV, ModifierFlag::NONE, KeyCode::F11, ModifierFlag::SHIFT_L
__KeyToKey__ ConsumerKeyCode::MUSIC_PLAY, ModifierFlag::NONE, KeyCode::F8