I can\'t believe that neither a Google or SO search has turned up a definitive answer or even much discussion for this, but:
Is it possible to edit/customize keyboar
I did this with Karabiner. I'm using a full size keyboard (F1-F19 keys) so I mapped them to F13 to F16. This way the layout of the keys matches the layout of the buttons in Chrome. Keymap file:
CHROME
com.google.Chrome
-
CHROMEDEBUGGINGKEY
This maps the F13-F16 keys to Chrome debugging keys
private.swap_chrome_to_debug_settings
CHROME
__KeyToKey__
KeyCode::F13, KeyCode::F8
__KeyToKey__
KeyCode::F14, KeyCode::F10
__KeyToKey__
KeyCode::F15, KeyCode::SEMICOLON, ModifierFlag::COMMAND_L
__KeyToKey__
KeyCode::F16, KeyCode::SEMICOLON, ModifierFlag::COMMAND_L, ModifierFlag::SHIFT_L,