Upload new APK to Alpha
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Many hints spread across the comments above but these steps are what (FINALLY) worked for my Android (Cordova) app as of 11/2019:
Increment Android Build/Version Number in Manifest (if necessary)
Run cordova build android
Open project in Android Studio
Run Build > Clean Project
Run Build > Generated Signed Bundle / APK
Fill out dialogs and ONLY check the "V1 JAR" sign checkbox - did not check the "V2 Full APK Signature" checkbox.
Upload APK to Google Play Dashboard
Cross your fingers