Here's a couple of recommendations I can make:
node-amqp: A RabbitMQ client that I have successfully used in combination with Socket.IO to make a real-time multi-player game and chat application amongst other things. Seems reliable enough.
zeromq.node: If you want to go down the non-brokered route this might be worth a look. More work to implement functionality but your more likely to get lower latency and higher throughput.
