There is a good book on the subject: "Twisted Network Programming Essentials", by Abe Fettig. The examples show how to write very Pythonic code, and to me personally, do not strike me as based on a bloated framework. Look at the solutions in the book, if they aren't clean, then I don't know what clean means.
My only enigma is the same I have with other frameworks, like Ruby. I worry, does it scale up? I would hate to commit a client to a framework that is going to have scalability problems.
