When you create an empty WinForms application with Visual Studio, the template has the STAThread attribute in the main application class.
1. Why is this attribute added?
Because it is required by the ActiveX object model. And you can drop ActiveX controls on a WinForm (so it is there for compatibility) OR some .NET classes use native controls which require that attribute.
2. What does it mean?
It means the thread runs in the single-threaded apartment model.
3. What happens if you remove this attribute?
If the attribute is removed, the behavior is undefined. The program may fail at random, with sometimes sensible error messages. For example, things may work now, then break with a service pack.