I am currently building a simple google chrome extension to prank my brother. The Extension simply deletes the old page and replaces it with HTML and CSS copied off of the \
According to Match Patterns, chrome is not a valid scheme.
chrome
scheme := '*' | 'http' | 'https' | 'file' | 'ftp'
You could use the following exclude_matches
exclude_matches
"exclude_matches": ["*://*/_/chrome/newtab*"]
You could also check if window.location.href contains chrome/newtab in you content scripts.
window.location.href
chrome/newtab