MySQL - NULL safe NOT equal operator

Question

I am just curious - I know about NULL safe equal operator <=>, but is there some NULL safe NOT equal operator? Or I have to always use something like this

Answer 1

I found that NOT (NULL <=> 1) works and I think it is also ISO standard compliant, but is cumbersome. A better way to show using column names would be like this: NOT (tbl.col1 <=> 1)