Use this to open any file with the default program:
import os
def openFile():
fileName = listbox_1.get(ACTIVE)
os.system("start " + fileName)
If you really want to use a certain program, such as notepad, you can do it like this:
import os
def openFile():
fileName = listbox_1.get(ACTIVE)
os.system("notepad.exe " + fileName)
Also if you need some if checks before opening the file, feel free to add them. This only shows you how to open the file.