I have a WinJS project that is previously built on Windows 8.1 using VS 2013.
Recently I upgraded this project to Universal Windows 10 by creating a blank Javascrip
In my case it was an issue with the configuration file web.config on my machine when I updated the newton version VS automatically fixed my web.config file to point to the new version. When I uploaded it to production the existing web.config was pointing to the old version.
Once I updated the web.config it started working again.