I am wondering if there are any ramifications in uploading files that are roughly 4GB in size through a web app using Django/Python? I remember in the past streaming uploads
For future readers: To up the max filesize allowed with in memory storage set the following in your settings.py:
settings.py
FILE_UPLOAD_MAX_MEMORY_SIZE = 5242880 # make it 5Mb instead of 2Mb
Of course this won't help you for 4Gb.