Using Panel or PlaceHolder

Question

What is the difference between and in ASP.NET?

When should you use one over the other?

Answer 1

I weird bug* in visual studio 2010, if you put controls inside a Placeholder it does not render them in design view mode.

This is especially true for Hidenfields and Empty labels.

I would love to use placeholders instead of panels but I hate the fact I cant put other controls inside placeholders at design time in the GUI.