How much of a pain is it to run a Django App on App Engine? Also, does the Datastore work as-is with Django?
App Engine includes version 0.96 of Django out-of-the-box, but it is quite crippled.
App Engine Helper and app-engine-patch supposedly fix this problem to some degree, but I haven't tried either myself.
http://code.google.com/appengine/articles/appengine_helper_for_django.html http://code.google.com/appengine/articles/app-engine-patch.html