I\'m trying to sign a Windows 8 appx package with a pfx file I have. I\'m using a command like so:
signtool.exe sign /fd sha256 /f \"key.pfx\" \"app.appx\"
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If you do not have to sign the app, right click on your project
Project Properties -> Signing -> uncheck "Sign the ClickOnce Manifest"
Also as this MS article suggests,
If you are using Visual Studio 2008 and are targeting .NET 3.5 and using automatic updates, you can just change the certificate and deploy a new version,