If you have two __m256d vectors x1 and x2 that each contain four doubles that you want to horizontally sum, you could do:
__m256d x1, x2;
// calculate 4 two-element horizontal sums:
// lower 64 bits contain x1[0] + x1[1]
// next 64 bits contain x2[0] + x2[1]
// next 64 bits contain x1[2] + x1[3]
// next 64 bits contain x2[2] + x2[3]
__m256d sum = _mm256_hadd_pd(x1, x2);
// extract upper 128 bits of result
__m128d sum_high = _mm256_extractf128_pd(sum1, 1);
// add upper 128 bits of sum to its lower 128 bits
__m128d result = _mm_add_pd(sum_high, _mm256_castpd256_pd128(sum));
// lower 64 bits of result contain the sum of x1[0], x1[1], x1[2], x1[3]
// upper 64 bits of result contain the sum of x2[0], x2[1], x2[2], x2[3]
So it looks like 3 instructions will do 2 of the horizontal sums that you need. The above is untested, but you should get the concept.
