I have a puzzle site and its an awful way of cheating. Its okay if only partially, but can it be done?
Something I had in mind was replacing the letters with images, but
You can disable the keyboard shortcut in most browsers (IE9, Firefox, Chrome, Opera), but you can't stop someone using Find by clicking it in the browser.
Here's some jQuery-powered JavaScript that does it:
$(window).keydown(function(e){
if ((e.ctrlKey || e.metaKey) && e.keyCode === 70) {
e.preventDefault();
}
});
Taken from http://caniuse.com/, where this feature regularly irritates me. On that site, it's used to make CTRL+F do a custom search on the page, instead of disabling it completely.