I\'ve just started working with Cassandra (datastax), version 2.1.3 and cqlsh version 5.0.1.
Cassandra starts up fine and the cluster is operational instantly.
First, you need to check the port 9042 whether this open or not if open then check below things like rpc_address and listen_address. you should set the server own IP address instead 0.0.0.0 or 127.0.0.1.
If all okay then please run below command to connect cqlsh.
cqlsh IP address 9042
If you enable authentication and authorization you have to put user/pass with this command.