I need to dynamically set values on a bunch or properties on an object, call it a transmission object.
There will be a fair number of these transmission objects that
Use Delegate.CreateDelegate to turn a MethodInfo into a strongly-typed delegate. This can improve performance massively. I have a blog post about this with sample code. Note that this is only going to help if you need to set the same properties multiple times - basically it means that a lot of the type checking is done once when you create the delegate, rather than on every invocation.
Marc Gravell has a HyperPropertyDescriptor project which achieves even better performance, but introduces an extra dependency. This project became the jumping off point for the more modern Fast Member (github). In general you would use Fast Member over HyperProperty.