How do I make an area unclickable with CSS?

Question

Let\'s say if I have wrapper div which includes some links and images, is there any way I can deactivate it at once with CSS only?

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After review of answers:

Answer 1

These days you can just position a pseudo-element over the content.

.blocked
{
    position:relative;
}
.blocked:after
{
    content: '';
    position: absolute;
    left:0;
    right:0;
    top:0;
    bottom:0;
    z-index:1;
    background: transparent;
}

http://jsfiddle.net/HE5wR/27/