If you means to access status of particular user from ASP.NET.
so, you want to know if that person is available or not. add image link to this url.
Where skyname is the person that you want to show status.
To make a link for Skype's profile
Joe Doe's Profile
but if you want to do it other way e.g. Code-Behind - Then this link should provide all example you need - https://developer.skype.com/Docs/Skype4COM/Example?action=show
IUserCollection iusercollection = skype.SearchForUsers("echo123");
if (iusercollection.Count > 0)
{
Console.WriteLine(iusercollection[0].FullName);
}
List of all IUser interface can find at https://developer.skype.com/Docs/Skype4COMLib/IUser
Hope this helps