When is optimisation premature?

Question

As Knuth said,

We should forget about small efficiencies, say about 97% of the time: premature optimization is the root of all evil.

Answer 1

First, get the code working. Second, verify that the code is correct. Third, make it fast.

Any code change that is done before stage #3 is definitely premature. I am not entirely sure how to classify design choices made before that (like using well-suited data structures), but I prefer to veer towards using abstractions taht are easy to program with rather than those who are well-performing, until I am at a stage where I can start using profiling and having a correct (though frequently slow) reference implementation to compare results with.