There are companies that provide this service. Service bureaus that deal with mass mailing will scrub an entire mailing list to that it's in the proper format, which results in a discount on postage. The USPS sells databases of address information that can be used to develop custom solutions. They also have lists of approved vendors who provide this kind of software and service.
There are some (but not many) packages that have APIs for hooking address validation into your software.
However, you're right that its a pretty nasty problem.
http://www.usps.com/ncsc/ziplookup/vendorslicensees.htm
