Attempting to use a FileUpload or AsyncFileUpload control in an updatepanel on a NET 4.5/C# web application.
I\'ve tried using either standard Scriptmanager or ToolK
File Upload will not work with a partial post back. It requires full page request. So add the below line in your page load.
ScriptManager.GetCurrent(this).RegisterPostBackControl(this.YourControlID);