I have two C# applications and I want one of them send two integers to the other one (this doesn\'t have to be fast since it\'s invoked only once every few seconds).
You can try .NET Remoting. Here is a simple example: CodeProject .NET Remoting.
If you are using .NET 3.5, you should go for WCF, as Remoting is slowly becoming obsolete. Again, there are many examples for WCF around.