Fastest Way to Delete a Line from Large File in Python

Question

I am working with a very large (~11GB) text file on a Linux system. I am running it through a program which is checking the file for errors. Once an error is found, I need

Answer 1

Update: solution using sed as requested by poster in comment.

To delete for example the second line of file:

sed '2d' input.txt

Use the -i switch to edit in place. Warning: this is a destructive operation. Read the help for this command for information on how to make a backup automatically.