In the database, I have various alpha-numeric strings in the following format:
10_asdaasda 100_inkskabsjd 11_kancaascjas 45_aksndsialcn 22_dsdaskjca 100_skdn
You can use regular expressions with substrings
order by substring(column, '^[0-9]+')::int, substring(column, '[^0-9]*$')