When I toggle on the install via USB in developer mode:
i had same problem with MI Redmi 4a i solved it by ->
first become a developer by clicking on
setting->About phone->MIUI version (7-8 times)
then, setting->additional setting->developer options->USB debugging
Turn on your usb debugging, then in developer options go for last item name is 'Turn on MIUI optimization', turn off this option it will ask for reboot , then reboot device by clicking Turn off & reboot button
after reboot go to Setting->Permissions click on top right menu button Turn on install via USB option
thats it !