Cannot obtain value of local or argument as it is not available at this instruction pointer, possibly because it has been optimized away

Question

Visual Studio 2010 kills (there is no other word) data in one of the arguments of the function in the unsafe block. What could cause this error? The following message shows

Answer 1

For web applications there is another issue which is important and it is selecting correct configuration during application publish process.

You may build your app in debug mode, but it might happen you publish it in release mode which omptimzes code by default but IDE may mislead you since it shows debug mode while published code is in release mode. You can see details in below snapshot: