How to select all columns, except one column in pandas?

Question

I have a dataframe look like this:

import pandas
import numpy as np
df = DataFrame(np.random.rand(4,4), columns = list(\'abcd\'))
df
      a         b                


        

Answer 1

You can use df.columns.isin()

df.loc[:, ~df.columns.isin(['b'])]

When you want to drop multiple columns, as simple as:

df.loc[:, ~df.columns.isin(['col1', 'col2'])]