Use them all the time to process long-running operations asynchronously. A web user won't want to wait for more than 5 seconds for a request to process. If you have one that runs longer than that, one design is to submit the request to a queue and immediately send back a URL that the user can check to see when the job is finished.
Publish/subscribe is another good technique for decoupling senders from many receivers. It's a flexible architecture, because subscribers can come and go as needed.
