I think this is the most popular way to do it before:
https://pytools.codeplex.com/wikipage?title=NumPy%20and%20SciPy%20for%20.Net
But this link is no longer
Updated Instructions July 2019:
I was able to get scipy up and running in IronPython but wasn't able to follow @Nilser's instructions completely. Here are some updated instructions to get it working.
Like others have said, the repo is now at http://code.enthought.com/.iron/eggs/index.html. Don't bother signing up for an Enthoughts account to access the old link, like some of the above comments suggest.
The ironpkg-1.0.0.py file is no longer hosted in Enthought's repo for some reason. I was able to track it down and am hosting it on github so it's easier to find.
ipy ironpkg-1.0.0.py --install. Check whether the install worked using ironpkg -h.c:\users\\.ironpkg . Also note that this is a system file, so you have to show system files in order to see it. Open it in a textpad and update the address. Should be: IndexedRepos = [
'http://code.enthought.com/.iron/eggs',
]
ironpkg scipy to install scipy and its dependencies.ipy -X:Frames -c "import scipy"