Does the order of conditions in a WHERE clause affect MySQL performance?

Question

Say that I have a long, expensive query, packed with conditions, searching a large number of rows. I also have one particular condition, like a company id, that will limit t

Answer 1

No, the order should not make a large difference. When finding which rows match the condition, the condition as a whole (all of the sub-conditions combined via boolean logic) is examined for each row.

Some intelligent DB engines will attempt to guess which parts of the condition can be evaluated faster (for instance, things that don't use built-in functions) and evaluate those first, and more complex (estimatedly) elements get evaluated later. This is something determined by the DB engine though, not the SQL.