Is there a way to search the latest version of every file in TFS for a specific string or regex? This is probably the only thing I miss from Visual Source Safe...
Another solution is to use "ctrl+shift+F". You can change the search location to a local directory rather than a solution or project. This will just take the place of the desktop search and you'll still need to get the latest code, but it will allow you to remain within Visual Studio to do your searching.