I\'m using django with apache and mod_wsgi and PostgreSQL (all on same host), and I need to handle a lot of simple dynamic page requests (hundreds per second). I faced with
Django 1.6 has added persistent connections support (link to doc for latest stable Django ):
Persistent connections avoid the overhead of re-establishing a connection to the database in each request. They’re controlled by the CONN_MAX_AGE parameter which defines the maximum lifetime of a connection. It can be set independently for each database.