The vast majority of simple applications should work just fine. As far as I can see, only applications that manually make use of pointers are at a risk. Indeed, if a pointer now is 64-bit, and you use it in calculations together with integers or cardinals (that are still 32-bit by default), you will get into trouble. I also think it is rather common that declarations for API functions that take pointers as arguments are using cardinals instead of the (unsigned) native integer type.
To make code that works well on any platform, one should use NativeUInts (IIRC, don't have a Deplhi compiler right now) instead of cardinals when working with pointers and integers simultaneously.
