I heard several times that jQuery\'s strongest asset is the way it queries and manipulates elements in the DOM: you can use CSS queries to create complex queries that would
If you are optimizing your page for IE8 or newer, you should really consider whether you need jquery or not. Modern browsers have many assets natively which jquery provides.
If you care for performance, you can have incredible performance benefits (2-10 faster) using native javascript: http://jsperf.com/jquery-vs-native-selector-and-element-style/2
I transformed a div-tagcloud from jquery to native javascript (IE8+ compatible), the results are impressive. 4 times faster with just a little overhead.
Number of lines Execution Time
Jquery version : 340 155ms
Native version : 370 27ms
You Might Not Need Jquery provides a really nice overview, which native methods replace for which browser version.
http://youmightnotneedjquery.com/
Appendix: Further speed comparisons how native methods compete to jquery
Array: $.inArray vs Array.indexOf: Jquery 24% slower
DOM: $.empty vs Node.innerHtml: Jquery 97% slower
DOM: $.on vs Node.addEventListener: Jquery 90% slower
DOM: $.find vs Node.queryselectorall: Jquery 90% slower
Array: $.grep vs Array.filter: Native 70% slower
DOM: $.show/hide vs display none: Jquery 85% slower
AJAX: $.ajax vs XMLHttpRequest: Jquery 89% slower
Height: $.outerHeight vs offsetHeight: Jquery 87% slower
Attr: $.attr vs setAttribute: Jquery 86% slower