Apache logs in mode debug:
[Tue Dec 21 11:36:33 2010] [info] [client 1.53.149.114] mod_wsgi (pid=24831, process=\'mysite\', application=\'mysite.com|\'): Loading
The daemon process crashed. See comments in the mod_wsgi FAQ about what causes crashes:
http://code.google.com/p/modwsgi/wiki/FrequentlyAskedQuestions
and follow links there.
Ultimately the cause can be many things, including loading incompatible mod_python at same time, using Python C extension module that doesn't work with sub interpreters, incompatible shared library versions used by Apache and/or extension modules in PHP etc.