There is a lot of information about new features and classes in new 4.0 however there are also changes that may affect existing applications, for example
Ti
I've just fixed a bug in a production app which recently moved to .NET 4.0.
Data binding that uses nested properties was throwing:
ArgumentException: Cannot bind to the property or column 'SomeProperty' on the DataSource.
It appears to be a known issue with a workaround. I couldn't find it on any official lists and the bug on Microsoft Connect has been closed as "Not Reproducible".
The nested properties are all defined in strings so I had to search for them all manually.