I need to patch the standard User model of contrib.auth by ensuring the email field entry is unique:
User._meta.fields[4].unique = True
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Since version 1.2 (May 11th, 2015) there has been a way to dynamically import any chosen registration form using the settings option REGISTRATION_FORM.
So, one could use something like this:
REGISTRATION_FORM = 'registration.forms.RegistrationFormUniqueEmail'
This is documented here.
And here's the link to the changelog entry.