My company has a website built in ASP.NET and targets .NET 3.5. It is too mangled and massive to be converted to .NET 4 in a timely manner. I am tasked with building a ticketing
Edit: As mentioned first port of call is to make sure each application has it's own application pool. Double and triple check this as a .net 3.5 site and a .net 4 site in the same app pool will cause the entire app pool to break.
Next, try remove the entire scripting section group, from my experience it solves it and i've not noticed any problems