My PHP/MS Sql Server 2005/win 2003 Application occasionally becomes very unresponsive, the memory/cpu usage does not spike. If i try to open any new connection from sql man
If your PHP app is holding open many SQL Server connections, then, as you may know, you have a problem with your app's database code. It should be releasing/disposing those connections after use and using connection pooling. Have a look here for a decent article on the topic...
http://www.c-sharpcorner.com/UploadFile/dsdaf/ConnPooling07262006093645AM/ConnPooling.aspx