I recently installed a bunch of dotfiles on my Mac along with some other applications (I changed to iTerm instead of Terminal, and Sublime as my default text editor) but eve
This occurred when I updated to Mac OS X Mavericks from Snow Leopard. I had to re-install brew beforehand too. Hopefully you ran the freeze command for your project with pip.
To resolve, you have to update the paths that the virtual environment points to.
brew install python
pip install --upgrade virtualenvwrapper
rmvirtualenv old_project
mkvirtualenv new_project
workon new_project
pip install -r requirements.txt
This should leave the project as it was before.