I have HTC Comet connected to Eclipse with SDK 2.2. I do a debug build - the application does not run; though it does get installed on the device. On the device I get this m
If your development environment is Windows make sure the USB drivers are correctly installed.
One way to ensure that the USB drivers are installed correctly is to get the PDANet Windows installer and let it install the USB drivers.
You can find the PDANet page here.