问题
What would be the negative effects of installing a legacy 32bit app into the C:\Program Files instead of the C:\Program Files(x86) ?
回答1:
I don't think it matters. You can run a 64-bit from your Desktop, an external drive, etc. the same way you can run a 32-bit app. I think the difference is purely for organization.
Or say you are developing a 32-bit and a 64-bit version of an application, you could install both of them and run them side by side by putting them in the separate Program Files folders.
回答2:
It could cause a problem based on what your application does.
For example, if your app queries for the Program Files folder, the WOW emulation layer will return Program Files (x86). Thus if you're trying to find things relative to where you're installed, you'll fail.
回答3:
None. I believe the two folders are there for organizational purposes only.
回答4:
None whatsoever. I do it all the time, and have never encountered any ill effects. I believe it's purely organizational.
回答5:
Probably none if the application that you want to install doesn't have a 64 bit parallel version.
If it has and you decide to install it, by default (if it is using the same folder names) it will overwrite the existing 32 bit application.
来源：https://stackoverflow.com/questions/752844/what-would-be-the-negative-effects-of-installing-a-32bit-app-into-the-c-program